Recent research has demonstrated the effectiveness of ssDNA as a homology-directed repair donor template, surpassing the capabilities of double-stranded DNA (dsDNA). ssDNA significantly enhances editing efficiency while reducing off-target effects, making it a versatile tool in various biological reactions and DNA nanotechnology applications. Tsingke now offers high-quality, sequence-validated ssDNA synthesis services to empower researchers in their gene editing endeavors. With our optimized ssDNA, you can achieve superior results and unlock new possibilities in genetic research.
Expanded Synthesis Range: Tailored ssDNA up to 6000 nt
Tsingke's single stranded dna synthesis service offers a wide range of customization options. We can synthesize ssDNA molecules up to 6000 nucleotides in length, providing you with the flexibility to design and engineer ssDNA templates that meet your specific research requirements. Our synthesis technology ensures high fidelity and accuracy, enabling you to work with longer ssDNA molecules for enhanced gene editing and DNA nanotechnology applications.
Minimized Cytotoxicity: Enhance Homologous Recombination Efficiency
By utilizing Tsingke's high-quality ssDNA, you can achieve higher homologous recombination and knock-in efficiency while minimizing cytotoxic effects. Compared to dsDNA, ssDNA offers a lower risk of random integration, making it particularly suitable for gene editing in primary cells, stem cells, and the creation of genetically modified animal models. With our ssDNA synthesis service, you can optimize your experiments and achieve precise genetic modifications without compromising cell viability.
Superior Editing Efficiency: Empowering CRISPR Gene Knock-In
Tsingke's ssDNA outperforms dsDNA as a homologous recombination template, delivering remarkable editing efficiency. In CRISPR and CRISPR-Cas9 genome editing experiments, our high-quality ssDNA serves as a potent donor template, enhancing both insertion and gene replacement efficiency. With 9-fold higher CRISPR/Cas9 gene knock-in efficiency compared to dsDNA, our ssDNA empowers researchers to achieve accurate and efficient gene editing outcomes, accelerating advancements in genetic research.
Conclusion
Tsingke's high-quality ssDNA synthesis service revolutionizes gene editing and DNA nanotechnology applications. With our expanded synthesis range, we offer tailored ssDNA up to 6000 nucleotides in length, providing you with the flexibility to design custom templates for your research needs. By utilizing our ssDNA, you can enhance homologous recombination efficiency while minimizing cytotoxic effects, enabling precise gene editing in various cell types. Our superior editing efficiency, with 9-fold higher CRISPR/Cas9 gene knock-in efficiency compared to dsDNA, empowers researchers to achieve groundbreaking results. Partner with Tsingke to elevate your gene editing experiments and unlock new possibilities in genetic research and DNA nanotechnology. With our high-quality ssDNA, you can pave the way for transformative advancements in the field of genetics.
