Gene Regulation

Home » Product & Services » Gene Regulation
Overview
Gene regulation modulates gene expression in cells and responds to environmental changes through mechanisms such as gene editing, overexpression, and molecular interactions. It involves regulation at multiple levels, including gene, transcription, and translation, playing a key role in processes like cell differentiation and development.

With advancements in technologies like CRISPR/Cas9, scientists can gain deeper insights into gene functions. Viral vectors such as lentivirus and adenovirus provide efficient solutions for gene delivery, widely used in gene therapy and research. Optimized viral vectors can precisely target specific cell types, improving the success rate of experiments and supporting long-term studies on gene function and drug responses. Meanwhile, products like sgRNA and Cas nucleases support precise gene editing, and molecular interaction analysis helps reveal the interactions between genes and proteins.

Tsingke, leveraging advanced R&D equipment and the advantages of the synthesis supply chain, drives down the cost of DNA synthesis through “Tsingke Gene Factory”. Tsingke Biotech focuses on cutting-edge life science technologies and is dedicated to providing efficient gene research tools for research institutions, hospitals, and biopharmaceutical companies, advancing scientific discoveries and pharmaceutical development.
Advantages
Service Type
Facility
Facility
Facility
Facility
Related Resource
FAQ
How to choose between AAV, LV, and ADV for different viral vector applications?
Adeno-associated virus(AAV):Suitable for long-term gene expression and applications with high safety requirements (e.g., gene therapy).
Advantages: Long-term expression, high safety.
Disadvantages: Lower transduction efficiency, small gene capacity.
Lentivirus(LV):Suitable for stable transduction and long-term gene expression (e.g., cell therapy).
Advantages: High transduction efficiency, broad cell type applicability, long-term expression.
Disadvantages: Potential genome integration, safety risks.
Adenovirus (ADV):Suitable for short-term expression and large-scale cell transduction (e.g., vaccine development).
Advantages: High transduction efficiency, suitable for large-scale production.
Disadvantages: Short-term expression, can trigger immune response.
Choose the appropriate vector based on your experimental needs.
What are the common methods for gene overexpression?
Common methods for gene overexpression:
Overexpression plasmids: Introduce the target gene into cells through plasmid transfection for overexpression.
Overexpression lentivirus: Use lentiviral vectors to stably transduce the target gene, suitable for long-term gene expression.
CRISPRa transcriptional activation system: Utilize CRISPR technology to activate the expression of endogenous genes, offering precise regulation.
Each method has its own characteristics, and the choice should be based on the experimental objectives and cell types.
*For Research Use Only. Not for use in diagnostic procedures.
Send Your Request
Want to learn more about these services? Speak to our experts and get a free quote.
Those with * are required
pop_close
pop_main
Subscribe to Our Newsletter
Stay updated with the latest industry news and expert insights. Subscribe now to receive:
        ● Industry updates
        ● Exclusive expert insights and analysis
Enter your email to stay ahead!