Cell therapy is a treatment method that uses biotechnological approaches to obtain cells with specific functions. These cells are then subjected to processes such as in vitro expansion and special cultivation to enhance their immune functions, and ability to kill pathogens and tumor cells. The goal is to treat a particular disease. Currently, the main types of cell therapy are immune cell therapy and stem cell therapy.
The cell therapy process involves understanding the disease mechanism, discovering and validating target genes, screening and optimizing drugs, and conducting preclinical and clinical trials. In the research phase, technologies like target enrichment, Next-Generation Sequencing (NGS), and quantitative Polymerase Chain Reaction (qPCR) identify potential therapeutic targets by screening disease-related genes. Target validation includes genomic studies, establishing cell and phenotype-based models, and using techniques like immunohistochemistry (IHC), fluorescence-activated cell sorting (FACS), Western blotting, and other antibody and recombinant protein technologies.
Tsingke provides a rich array of products and comprehensive support for researchers in cell therapy, facilitating exploration and innovation in the field of disease treatment. In the target discovery process, we offer molecular reagents, probes, and oligo products to assist in screening target genes. Additionally, we provide protein and antibody expression services to aid in target validation and analysis. In the drug discovery process, candidate molecule optimization is crucial. We offer high-quality gene synthesis, sgRNA synthesis, plasmid preparation, and other services to support drug screening and optimization.
